Prof. Rodolfo Negri
1981 As part of an exchange program between Italian universities and the National Institute of Health (NIH), he spends a three-month period of training on biological chemistry techniques in the laboratory of Dr. Harold Edelhoc in Bethesda - Maryland - U.S.A.
- 1982-1984 Carries out experimental work for his degree thesis in Biological Sciences at the University of Rome, La Sapienza, in the laboratory of Prof. Ernesto Di Mauro; thesis topic: The influence of DNA topology on transcription by RNA polymerase II.
- 1984 Degree in Biological Sciences at the University of Rome, La Sapienza. (summa cum laude).
- 1984-1987 Post-doctoral researcher position at the University of California in San Diego (UCSD) in the laboratory of Dr. E.P. Geiduschek. Topic of research carried out: the structure of RNA polymerase III transcription complexes in yeast. Part of the work carried out contributed to the understanding of the role of TFIIIB as a transcription initiation factor of RNA polymerase III, clarified for the first time by E.P.Geiduschek's group (Kassavetis et al., 1989).
- 1987-1989 CNR fellow in the laboratory of prof. Ernesto Di Mauro at the Study Center for Nucleic Acids in Rome. Research topic: Influence of chromatin structure and nucleosome positioning on the regulation of transcription in yeast. Some of the work done has shown the influence of DNA flexibility topology on nucleosome positioning (Negri et al., 1989; Costanzo et al., 1990).
- 1989-2001 CNR Researcher at the Nucleic Acids Study Center - Rome. Main research topic: Influence of chromatin structure and nucleosome positioning on transcription regulation in yeast. Part of the work carried out has produced the first clear identification of nucleosomes with multiple but rotationally correlated translational positions in vivo (Buttinelli et al.,1993; Buttinelli et al.,1995; Costanzo et al.,1995).
- Since November 2001 he has been full professor of Molecular Biology at the University of Rome, La Sapienza where he holds the Molecular Biology course for the three-year degree in Interfaculty Biotechnology of which from 2011 to 2017 he was Deputy Vice President of the Degree Course. He also holds the teachings of: Functional Genomics in the Master's Degree in Biotechnology and Genomics for Industry and the Environment and the course of Molecular Biology in the three-year degree in Bioinformatics of which he was co-founder and, from November 2017 to November 2022, President of the Degree Course.
In 2022 he was part of the Organizing Committee of the three-year degree course in Mathematical Sciences for Artificial Intelligence of the Faculty of MFN Sciences of Sapienza University of Rome.
- Since February 2002, having been designated by the committee of professors entrusted on behalf of the Dean of the Faculty, he has been scientific director of the Laboratory of Functional Genomics and Proteomics of Model Systems of the Faculty of Sciences MNF of the University of Rome, La Sapienza and has accumulated considerable experience in the use of methodologies based on next-generation sequencing (NGS) in Functional Genomics by collaborating on several projects of transcriptomics and broad-spectrum mapping of interactions between nucleic acids and proteins.
- From October 2002 to October 2006 he was a member of the board of the Italian Society of Biophysics and Molecular Biology (SIBBM).
- From June to December 2006 he was Associate Research Director of the CNRS at the Laboratory of Molecular Genetics of the Ecole Normal Supèrieure in Paris where he actively collaborated with the transcriptomics platform.
- From October 2009 to December 2013 he was the coordinator of the PhD course in Cellular and Developmental Biology at the University of Rome, La Sapienza.
- From January 2011 to March 2017 he was secretary and treasurer of the Italian Federation of Life Sciences (FISV) and had a leading role in the organization of the national Congresses in Rome (2012 and 2016) and Pisa (2014).
- From 2018 to 2020 he was a member of the Commission for Medium and Large Equipment of Sapienza University of Rome
- From 2021 to 2023 he was President of the scientific council of the cooperation program with Mozambique BIOFORMOZ: Support for Environmental Research (2020-2023) funded by the Italian Agency for Development Cooperation (AICS).
- Since 2023 he has been a member of the Epigenetic Society.
- Since November 2024 he has been Director of the Department of Biology and Biotechnology Charles Darwin of Sapienza University of Rome.
Contatti
Prof. Rodolfo Negri
Email: rodolfo.negri@uniroma1.it
Edificio di via Dei Sardi (RM024)
via dei Sardi 70 - 00185 - Roma