Our research group investigates on topics related to structure, function and evolution at multiple levels of biological organization, from molecules to cells, from organisms to populations and ecosystems. Some examples of specific subjects are: apoptosis and senescence, thyroid hormones and...
research
-
-
Analyses comparing transcriptomes to genomes of mammalian species have established that approximately two-thirds of genomic DNA is pervasively transcribed, in sharp contrast to the less than 2% that is ultimately translated into proteins. In particular, multicellular organisms are characterized...
-
Our main research lines are:
1 ) Role and mechanism of action of oligogalacturonides in plant-pathogen interactions (Prof. De Lorenzo)
2 ) Role of pectin in plant growth, development and bioconversion of biomass (Prof. Cervone)
3 ) Study of cell wall biochemical... -
Plants are an essential part of the natural world. The need for renewable energy, the ever increasing pressure for food and environment preservation are among the urgent challenges which require a better understanding of plant biology. In the Plant Development Laboratory (PDL), which consists of...
-
The research lines in neurobiology are focused on the molecular mechanisms of normal and pathological nerve functions. In particular: the cell biology of serpinopathies; the role of acetylcholine in glial cells; synaptic adhesion molecules in disorders of nervous system development; the pathway...
-
Our main research lines are: Analysis of the molecular mechanisms involved in host-pathogen interaction in intestinal or pulmonary bacterial infections. Characterization of pathways controlling virulence gene expression, biofilm formation, and host immune evasion in bacterial pathogens....
-
A significant array of unicellular as well as multicellular differentiated model systems is exploited for studying molecular and cellular aspects of human genetic diseases (mitochondrial pathologies, calcium homeostasis alterations) and the relationships between aging, apoptosis and oxidative...
-
Genetic information leads the entire physiological cell functioning. We study the nature of the genetic material and the molecular mechanisms that regulate gene expression.
Our approaches deal with the analyses of the ancient processes that produced the present informational molecules and,... -
The research projects carried out by our group fall into four main research fields: structure, function and integrity of chromatin, genetic control of cell division, molecular mechanisms of ageing and diseases, evolution. Different aspects of these broad topics are specifically analyzed, using...
-
Research in our Department aims at finding solutions to a wide range of complex biological questions, and covers a broad range of disciplines, including biochemistry, ecology molecular biology, structural biology, genetics, genomics, bioinformatics, cell biology, developmental biology, stem cell...