CERVONE FELICE CV

Allegato CV: 

19-12-1970: Laurea all'Università di Napoli .
1971-1972: Borsista MPI (Pubblica Istruzione) presso l’Istituto Internazionale di Genetica e Biofisica (CNR) di Napoli
1972-1980: Assistente Ordinario di Fisiopatologia Vegetale, Università di Napoli.
1977-1978: Borsista EMBO, Dipartimento di Botanica, Imperial College of Science and Technology di Londra.
1980-1990: Professore Associato di Fisiologia Vegetale, Università di Roma "La Sapienza".
1987-1988: Anno Sabbatico al “Complex Carbohydrate Research Center” afferente ai Dipartimenti di Biochimica e Botanica dell'Università della Georgia (U.S.A.).
1987: Borsista Fulbright all’Università della Georgia (USA)
1990 ad oggi: Professore Ordinario di Fisiologia Vegetale presso "La Sapienza”.
1996-98: Editore Associato della Rivista Internazionale “Molecular Plant-Microbe Interactions”.
1999-02: Membro del Consiglio Scientifico del Centro di Biologia Molecolare (CNR), Roma.
2002-04: Membro del Consiglio Scientifico dell’ Istituto di Biologia Forestale e Ambientale (CNR), Porano.
2004-06: Membro della Scholarship Advisory Committee dell’Armenise-Harvard Foundation, Boston.
2004: Presidente del X Cell Wall Meeting
2004-2010: Presidente della Società Italiana di Biologia Vegetale (già Società Italiana di Fisiologia Vegetale)
2005-2009: Presidente del Consiglio di Area Didattica di Biologia della Sapienza.
2009: Membro del Panel di Biologia per la valutazione dei laboratori del CNR sul Territorio Nazionale.
2009: Riceve il prestigioso “Research Advanced Grant” (2,1 milioni di euro) dall’European Research Council.
2009-2012: Presidente dell’International Society of Plant-Microbe Interactions
2011-oggi: Presidente della Federazione Italiana di Scienze della Vita

Profilo scientifico. Dopo l’iniziale attività di ricerca in Biochimica e Biologia Molecolare l’interesse scientifico del Prof. Cervone ha riguardato le basi dell’ immunità innata delle piante e il ruolo della parete cellulare nella resistenza alle malattie e nella crescita e sviluppo delle piante. L’intensa attività di ricerca del Prof. Cervone è documentata non solo da pubblicazioni su prestigiose riviste e da interventi su invito a congressi e seminari internazionali, ma anche dal fatto che i suoi progetti di ricerca sono stati regolarmente finanziati dalla Comunità Europea e da numerose Istituzioni e Fondazioni Nazionali e Internazionali. Recentemente ha ricevuto un prestigioso Grant dallo European Research Council (ERC Advanced Grant). Nel suo laboratorio hanno lavorato qualificati studenti di Dottorato e studiosi post-Dottorato italiani e stranieri, molti dei quali hanno continuato con successo la loro carriera scientifica in Italia e all’estero. E’ autore di più di centoventi pubblicazioni e brevetti.

13-10-1947: Born in Cimitile (Naples-Italy).
December 1970: Laurea Degree (Doctor) in Biological Chemistry at The University of Naples.
1971-72: Post-Doctoral Fellowship at The International Institute of Genetics and Biophysics (Naples).
1972-80: Assistant Professor of Physiological Plant Pathology at The University of Naples
1977-78: EMBO fellowship at The Botany Department of The Imperial College of Science and Technology (London -U.K.)
1980-90: Associate Professor of Plant Physiology at the University of Rome "La Sapienza"
1987-88: Visiting Scientist at The Complex Carbohydrate Research Center (CCRC-Departments of Botany and Biochemistry of The University of Georgia-U.S.A.).
1999: Fulbright fellowship at the CCRC
1990-today: Full Professor of Plant Physiology at the University of Rome "La Sapienza".
1996-98: Served as Associate Editor of the Journal “Molecular Plant-Microbe Interactions”.
1999-02: Served as a member of the Advisory Board of the Center of Molecular Biology, Italian Research Council, Rome.
2002-04: Served as a member of the Advisory Board of the Institute of Environmental and Forrest Biology, Italian Research Council, Rome.
2004-06: Served as a member of the Scholarship Advisory Committee of the Armenise-Harvard Foundation, Boston.
2004: Chairman of the X Cell Wall Meeting
2005-today: Chairman of the Biology Faculty Professors at the University of Rome “La Sapienza”.
2006-today: President of the Italian Society of Plant Physiology.
2008: Received a Grant from The European Research Council
2009-2012: President of the International Society for Plant-Microbe Interactions (IS-MPMI)
2011-today: President of the Italian Federation of Life Science

Scientific Profile. After the initial training in Biochemistry and Enzymology, his activity was focused on the plant innate immunity and on the role of the cell wall in the resistance against microbes and in plant development. As a plant biologist Prof. Cervone has an excellent track record of over 3500 citations (ISI). He has been invited speaker in many National and International Meetings and has given seminars in many International Institutions. He received important research grants from the European Community, the National Research Council, the Ministry of public Education, the Ministry of Agriculture and the Foundation Pasteur-Cenci Bolognetti. In 2008 he was recipient of a prestigious grant from the European Research Council (ERC-Advanced Grant) to study and exploit the strategies of microrganisms to improve fuel production from biomass. Prof. Cervone has a long experience in teaching Plant Physiology and Biotechnology. He had an intense activity in teaching research and his laboratory has attracted first quality students and post docs. Many of them have successfully continued their scientific career.

Elenco delle più rilevanti pubblicazioni del Prof. Felice Cervone negli ultimi 5 anni

1) Bonivento D, Pontiggia D, Di Matteo A, Fernandez-Recio J, Salvi G, Tsernoglou D, Cervone F, De Lorenzo G, Federici . (2008) Crystal structure of the endopolygalacturonase from the phytopathogenic fungus Colletotrichum lupini and its interaction with polygalacturonase-inhibiting proteins. Proteins. 70, 294-299.

2) Ferrari S, Galletti R, Pontiggia D, Manfredini C, Lionetti V, Bellincampi D, Cervone F, De Lorenzo G (2008) Transgenic expression of a fungal endo-polygalacturonase increases plant resistance to pathogens and reduces auxin sensitivity. Plant Physiology. 146, 669-681.

3) Casasoli M, Spadoni S, Lilley KS, Cervone F, De Lorenzo G, Mattei B (2008) Identification by 2D-DIGE of apoplastic proteins regulated by oligogalacturonides in Arabidopsis thaliana. Proteomics 8, 1042-1054.

4) Casasoli M, Federici L, Spinelli F, Di Matteo A, Vella N, Scaloni F, Fernandez-Recio J, Cervone F, De Lorenzo G (2009) Integration of evolutionary and desolvation energy analyses identifies functional sites in a plant immunity protein. Proc.Natl.Acad.Sci.U.S.A 106, 7666-7671.

5) Spinelli F, Mariotti L, Mattei B, Salvi G, Cervone F, Caprari C (2009) Three aspartic acid residues of polygalacturonase-inhibiting protein (PGIP) from Phaseolus vulgaris are critical for inhibition of Fusarium phyllophilum PG. Plant Biology 11, 738-743.

6) Lionetti V, Francocci F, Ferrari S, Volpi C, Bellincampi D, Galletti R, D’Ovidio R, De Lorenzo G, Cervone F (2010) Engineering the cell wall by reducing de-methyl-esterified homogalacturonan improves saccharificatio of plant tissues for bioconversion. Proc.Natl.Acad.Sci.U.S.A. 107, 616-621.

7) Brutus A, Sicilia F., Macone A., Cervone F., De Lorenzo G. (2010) A domain swap approach reveals a role of the plant wall-associated kinase 1 (WAK1) as a receptor of oligogalacturonides. Proc.Natl.Acad.Sci.U.S.A. .107, 9452-9457

8) Raiola A, Lionetti V, Elmaghraby I, Immerzeel P, Mellerowicz EJ, Salvi G, Cervone F, Bellincampi D (2011) Pectin methylesterase is induced in Arabidopsis upon infection and is necessary for a successful colonization by necrotrophic pathogens. Mol Plant Microbe Interact. 24, 432-40

9) De Lorenzo G, Brutus A, Savatin DV, Sicilia F, Cervone F. (2011) Engineering plant resistance by constructing chimeric receptors that recognize damage-associated molecular patterns (DAMPs). FEBS Lett. 585, 1521-1528.

10) Benedetti M, Leggio C, Federici L, De Lorenzo G, Pavel NV, Cervone F. (2011) Structural resolution of the complex between a fungal polygalacturonase and a plant polygalacturonase-inhibiting protein by small-angle X-ray scattering. Plant Physiol. 157, 599-607.

11) Lionetti V., Cervone F. and Bellincampi D. (2012) Methyl esterification of pectin plays a role during plant-pathogen interactions and affects plant resistance to diseases. Journal of Plant Physiology, 169: 1623-1630.

12) Borras-Hidalgo O., Caprari C., Hernandez-Estevez I., De Lorenzo G. and Cervone F. (2012) A gene for plant protection: expression of a bean polygalacturonase inhibitor in tobacco confers a strong resistance against Rhizoctonia solani and two oomycetes. Frontiers in Plant Science, 3: 268-273.

13) Reca IB, Lionetti V, Camardella L, D'Avino R, Giardina T, Cervone F, Bellincampi D. (2012) A functional pectin methylesterase inhibitor protein (SolyPMEI) is expressed during tomato fruit ripening and interacts with PME-1. Plant Mol Biol. 79: 429-442.

14) Ferrari S, Savatin DV, Sicilia F, Gramegna G, Cervone F, De Lorenzo G. (2013) Oligogalacturonides: plant damage-associated molecular patterns and regulators of growth and development. Frontiers in Plant Science. 4: 49-57.

15) Suárez L, Savatin DV, Salvi G, De Lorenzo G, Cervone F, Ferrari S (2013) The non- traditional growth regulator Pectimorf is an elicitor of defense responses and protects Arabidopsis against Botrytis cinerea. Journal of Plant Pathology 95: 171-176.

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