Information and Regulation

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Genetic information leads the entire physiological cell functioning. We study the nature of the genetic material and the molecular mechanisms that regulate gene expression.
Our approaches deal with the analyses of the ancient processes that produced the present informational molecules and, in addition, the mechanisms that in modern cells accomplish of the aims of the genetic program in response to the environment or to stressful stimuli. We study the epigenetic processes acting at the chromatin level, the maintenance of the chromosome ends, the accurate DNA replication and cellular proteostasis. Phylosophical and historical aspects of knowledge about genetic information are also considered.